Dermatology

                                                                                                                       Robert M Rosen, D. O.

Rhinoscleroma

Mildly contagious

Always starts on nose

Central Europe/Central America

Mikulicz cells - large histiocytes with Klebs Rhiasclerom. - stains with giemsa, with silver, with PAS = Frisch bacilli

Russell bodies - giant, red, refractile plasma cells containing immunoglobulins, not 100 percent specific unless Mikulicz cells also; Russell also seen is other chronic disease: lues, DLE, SCC