Lichen
planus is a relatively common skin disease that comes in episodes
lasting months to years. The onset may be gradual or quick, but its
cause, like many skin diseases, is unknown. It appears to be a
reaction in response to more than one provoking factor. Theories
include stress, genetics, infective (viral hepatitis C) and
immunologic (autoimmune). There are also drugs that produce lichen
planus-like allergic reactions to high blood pressure, heart disease,
and arthritis medications. There is an inherited form also which is
often more severe and can have a protracted course.
Lichen planus appears as shiny, flat-topped bumps that often have
an angular shape. These bumps have a reddish-purplish color with a
shiny cast due to a very fine scale. The disease can occur anywhere on
the skin, but often favors the inside of the wrists and ankles, the
lower legs, back, and neck. The mouth, genital region, hair and nails
are affected in some individuals. Thick patches may occur, especially
on the shins. Blisters may rarely occur. Bumps may appear in areas of
trauma on some individuals. About 20 percent of the time lichen planus
of the skin causes minimal symptoms and needs no treatment. However,
in many cases the itching can be constant and intense.
This disease occurs most often in men and women between the ages of
30 and 70 years. It is uncommon in the very young and elderly. All
racial groups seem susceptible to lichen planus.
There is no known cure for skin lichen planus. but treatment is
often effective in relieving itching and improving the appearance of
the rash until it goes away. Since every case of lichen planus is
different, no one treatment does the job. Topical corticosteroids are
very useful. Antihistamines may be prescribed to relieve itching.
Extensive cases may require the use of oral corticosteroid (cortisone,
prednisone) for a number of weeks. This usually shortens the duration
of the outbreak. For severe cases powerful treatments include photo
chemotherapy light treatment (PUVA), the retinoids drugs (Soriatane
and Accutane), Neoral and Plaquenil.
Other helpful measures include soothing baths (Aveeno Colloidal
Oatmeal, Nutrasoothe) and the application of wet dressings (tap water,
Burows solution 1:40) to the affected areas to help reduce itching.
Also, the use of lotions containing anti-itch ingredients such as
menthol, pramoxine and phenol (Sarna, Aveeno cream, Prax, Itch-X) may
be helpful.
As it heals, lichen planus often leaves a dark brown discoloration
of the skin. Like the bumps themselves, these stains may eventually
fade with time without treatment. About one out of five people will
have a second attack of lichen planus.
Special cases
Lichen Planus of the Mouth
Lichen planus of the mouth most commonly affects the inside of the
cheeks, gums and tongue. Oral lichen planus is more difficult to treat
and typically lasts longer than skin lichen planus. Fortunately, most
cases of lichen planus of the mouth cause minimal problems. About a
third of all people who have oral lichen planus also have skin lichen
planus. Women may also have lichen planus of the vaginal area.
Oral lichen planus typically appears as patches of fine white lines
and dots. These changes usually do not cause symptoms. Dentists during
routine check-ups often find them. More severe forms of oral lichen
planus can cause painful sores and ulcers in the mouth.
Often a biopsy of affected tissue is needed to confirm a diagnosis
of lichen planus. Sometimes, several biopsies are needed at various
times, along with blood tests. It is common for a yeast infection to
be present with lichen planus. In these cases, the yeast infection is
usually treated first. The treatment often improves the lichen planus.
There have been cases of lichen planus like allergic reactions to gold
and mercury in dental materials but they are rare.
When lichen planus is very severe, especially if the underside of
the tongue is involved, there is a slightly increased risk of
developing oral cancer. If this is present, avoid the use of alcohol
and tobacco products, which also increase the risk. Schedule visits to
the dentist and exams for oral cancer at least twice a year.
Nail Involvement
Nail changes have been reported in about 10 percent of lichen
planus cases. The majority of nail changes result from damage to the
nail matrix, or nail root. Usually only a few fingernails or toenails
are involved, but occasionally are all affected. Nail changes
associated with lichen planus include longitudinal riding and
grooving, splitting, nail thinning and nail loss. In severe cases, the
nail may be temporarily or permanently destroyed.
Hair Involvement
Lichen Planopilaris is the specific name given to lichen planus on
the scalp that causes permanent scarring alopecia with inflammation
around affected hair follicles. It mostly affects middle-aged adults
as distinct patches of hair loss. Treatment includes oral
steroids (to get it under quick control) plus topical steroid liquids and the oral medications Accutane
or Plaquenil.